In disposable medical gloves, sterilization with ethylene oxide is one of the common methods of disinfecting medical gloves. This method is a mature process, suitable for large-scale production of medical gloves.
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Ethylene oxide sterilization is a method of fumigating disinfected objects using ethylene oxide gas to achieve the effect of sterilization. Generally, ethylene oxide used for sterilization is a broad-spectrum sterilant. It can kill various microorganisms at room temperature, including spores, tubercle bacillus, bacteria, viruses, fungi and so on.
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The principle is through this gas and the thiol group (-SH), amino group (-NH2), hydroxyl group (-OH) and carboxyl group (-COOH) on the protein molecule on the microorganism and the imino group (-NH-) on the nucleic acid molecule An alkylation reaction occurs, causing the microbial protein to lose reactive groups, hindering the normal biochemical reaction and metabolism of the protein, and ultimately the microbial death, thereby achieving a sterilization effect.
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The advantages of ethylene oxide sterilization are that it is carried out at room temperature, has strong sterilization power, has a wide sterilization spectrum, and has very little damage to articles. Therefore, the current ethylene oxide sterilization is also a commonly used sterilization method in medical devices.
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Using this sterilization method on medical gloves does not have a significant impact on the protective effect of the gloves, and can reach the corresponding sterilization standards, which is worthy of popularization and use.
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For the production of disposable sterilized medical gloves, there are currently two sterilization methods: ethylene oxide sterilization and gamma ray sterilization. Their purpose is to kill the microorganisms on the glove and make it reach a range. Play a sterile and safe effect in use.
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1. Principle of sterilization
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Ethylene oxide sterilization is one of the chemical sterilization methods. Ethylene oxide is one of such broad-spectrum sterilizing agents. It utilizes the ability to interact with carboxyl groups (-COOH) and amino groups (- NH3), hydroxyl (-OH), etc. react to inactivate the protein and cause the death of microorganisms, thus achieving the purpose of sterilization.
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After gamma ray sterilization, the chemical substance (DNA) of the microorganisms on the sterilized object will change and the cell activity will be lost after radiation irradiation, so as to achieve the purpose of sterilization. It is one of the radiation sterilization methods.
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2. Operation steps
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Ethylene oxide sterilization includes a series of steps such as pretreatment, evacuation, gas addition, gas action process, and gas exchange. The gamma-ray sterilization process is composed of two parts: sterilization verification and irradiation process. Before the work begins, the operability of the sterilization environment, sterilization equipment, and sterilization products in the sterilization process is confirmed. Irradiation process can be carried out.
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3. Follow-up treatment of gloves
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After the ethylene oxide sterilization is completed, the gloves need to be left for a period of time, and the subsequent processes can be processed after the gas has dissipated. And after the gamma ray sterilization, there is no need to wait, and the subsequent processing action can be carried out immediately.
Post time: Apr-28-2020